Education

1976 – 1982 : Secondary School (Stedelijk Gymnasium Utrecht)
1983 – 1989 : Medical Doctor, University of Utrecht
1984 : Anatomy Student Assistant
1987 : ECFMG-I (American Doctors Exam) Scientific Research, Edinburgh
1988 : Doctorate Medicine RUU
1990 : Doctors Exam
1990 : ECFMG-II (American Doctors Exam)
1990 – 1991 : Resident Cardiology, St. Antonius Hospital, Nieuwegein
1991 – 1993 : Resident Internal Medicine, St. Antonius Hospital, Nieuwegein
1993 – 1996 : Resident Cardiology, St Antonius Hospital, Nieuwegein
1996 : Registration as Cardiologist
1996–1999 : Fellowship Interventional Cardiologie St Antonius Hospital, Nieuwegein
2001 : Thesis "Oral Anticoagulation in Percutaneous Coronary Intervention” State University, Nijmegen. Promotor Prof FWA Verheugt.
2002 : Eindhoven prize for best thesis 2001
2003 : Member Concilium Cardiologicum
2006 : ICH-GCP training
2006 :  Editor Future Cardiology
2007 : Member of Thrombosis Working Group of ESC
2007 : Fellow of the ACC
2007-11 : Editor Health Direct Cardiology
2007-11 : Board member Netherlands Society of Vascular Medicine
2008 : Member Working group on Acute Cardiac Care of ESC
2008-2011 : Chair Committee ICCU NVVC
2008 : Fellow of the ESC
2009 : Working Group of ACS and Interventional Cardiology NVVC
2010 : Working Group National Registry ACS
2011-16 : Nucleus Working group Thrombosis ESC
2012-14 : Program Committee ESC (CPC)
2012 : Working group Trans catheter Valve of the NVVC
2012-14 : Working group Press ESC
2013 : Press Coordinator scientific sessions ESC Amsterdam
2016 : ICH-GCP training
2013 : Lid Wetenschappelijke adviesraad St Antonius Ziekenhuis
2016-2018 : Program Committee ESC (CPC)
2016-2017 : MSc Health Economics at the London School of Economics
2018 : Associate Professor Cardiology UMCG
2018 : Associate Editor Netherlands Heart Journal
2019-2020 : Coordinator ACS program committee ESC (CPC)

Guidelines and position papers:
2013 : Official content reviewer 2014 ESC Guidelines on revascularisation
2014 : Management of antithrombotic therapy in atrial fibrillation patients presenting with acute coronary syndrome and/or undergoing percutaneous coronary or valve interventions:  a joint consensus document of the European Society of Cardiology Working Group on Thrombosis, European Heart Rhythm Association (EHRA), European Association of Percutaneous Cardiovascular Interventions (EAPCI) and European Association of Acute Cardiac Care (ACCA) endorsed by the Heart Rhythm Society (HRS) and Asia-Pacific Heart Rhythm Society (APHRS)
2014 : Aspirin therapy in primary cardiovascular disease prevention: a position paper of the European Society of Cardiology working group on thrombosis
2015 : Antithrombotic therapy in the elderly: expert position paper of the European Society of Cardiology Working Group on Thrombosis
2016 : Official content reviewer 2017 ESC Guidelines on the diagnosis and treatment of peripheral artery diseases
    Official content reviewer 2017 ESC Guidelines management of acute myocardial infarction in patients presenting with STEMI
    Official content reviewer of the 2017 ESC Focused Update on Dual Anti-platelet Therapy
2016 : Oral anticoagulants in coronary heart disease (Section IV). Position paper of The ESC Working Group on Thrombosis – Task Force on Anticoagulants in Heart Disease
2017 : Management of antithrombotic therapy after bleeding in patients with coronary artery disease and/or atrial fibrillation: expert consensus paper of the European Society of Cardiology Working Group on Thrombosis 2017
2019 : Chair position paper ESC antithrombotic management in patients undergoing TAVI

Work Experience

1996 – 1999 : Chef de Clinique and Fellow Interventional Cardiology, St. Antonius Hospital
2000 : Staff Cardiologist, St. Antonius Hospital
Member Medical Staff, St. Antonius Hospital
Medical director of Cardiac Care Unit, Director of R&D department, Ad interim director of the Catheterization Laboratory
2002-2007 : Chairman Committee on CPR, St Antonius Hospital
2003 : Ad interim director of training program of Cardiology St Antonius Hospital
2005 : Member committee emergency physician St Antonius Hospital
2006 : Head of the St Antonius Center for Platelet Function Studies
2011 : Director of training program of Cardiology in the St Antonius Hospital

Expertise

• Interventional cardiology including ASD/PFO closure, TAVI, percutaneous PVL closure, alcohol ablation for HOCM
• Treatment of HOCM
• Antithrombotic treatment (CAD/PCI/AF)

Peer-reviewed Publications
· Total publications on PUBMED :  367
· Publications Web of Science : 422
· H-index of Science : 53
· Total citations Web of Science : 17.97

Invited lectures (ESC, ACC, TCT, Eurothrombosis, etc) > 200

Teaching (Director of training)

• Weekly teaching cardiologist in training
• Weekly teaching coassistenten
• COIG teaching for Cardiology

Grants
· 2000 PI for the Netherlands, FP7-HEALTH-2010-single-stage “Reducing stent thrombosis”: PRESTIGE (PREvention Stent Thrombosis by an Interdisciplinary Global European effort) (2000)
· 2011 PI: Innovatiefonds St Antonius Hospital for POPular risk score: 200K
· 2011 Co-PI: ZonMw subsidie doelmatigheid genetica for POPular Genetics: 570K
·  2013 PI: ZonMw subsidie doelmatigheid antiplaatjes therapie bij ouderen: 470K
·  2014 PI: Antiplatelet treatment in patients undergoing CABG: 1. 5 M (ASTRA ZENICA)
· 2015: Wetenschapsfonds St Antonius Hospital PRESTIGE II; 61K.
·  2016 PI: International registry POPular age (ASTRA Zenica 470K)
· 2016 St Antonius Wetenschaponds 40K
· 2017: Wetenschapsfonds St Antonius Hospital PACIFIC  43K
· 2018: Wetenschapsfonds St Antonius Hospital pre-hospital HEART-score 56K
2018 PI: PACIFIC trial duration of DAPT (ASTRA ZENECA 277K)

Thesis supervisions from St Antonius Hospital
2009  JW van Werkum, Platelets and stent thrombosis.
2010   A Heestermans, Antiplatelet therapy in myocardial infarction and coronary stent thrombosis.
2011  NJ Breet, Predictive value of platelet function testing.
2012  H Bouman, Towards personalized antiplatelet therapy.
2014  W. Dewilde, Oral Anticoagulants in patients undergoing PCI. The WOEST study.
2015  R Steggerda, Treatment of patients with HOCM
2017  P Janssen Antiplatelet therapy in patients undergoing CABG
2017  T Godschalk Stent thrombosis
2018  M Liebregts Alcohol Septal Ablation

Currently thesis supervision
T. Bergmeijer Platelets and genetics in PCI
N. Bennaghmouch (N)OAC’s in patients undergoing PCI
M. Gimbel Antiplatelet therapy in patients over 70 years of age
V. Nijenhuis Anticoagulation in patients undergoing TAVI
L. Willemsen Antiplatelet treatment in patients undergoing CABG
B. Swinkels Long term follow-up of aortic valve surgery
K. Zheng FAMOUS study: triage of chest pain patients at home
D. Chan Pin Yin Optimal duration of DAPT after stenting
A de Veer NOACs

Awards
J.M. ten Berg: Eindhoven dissertatie prijs Netherlands Society of Cardiology best thesis 2001
J.W. Van Werkum: Vasculaire Biologie Jaarprijs Netherlands Society of Cardiology 2009
N.J. Breet: Vasculaire Biologie Jaarprijs Netherlands Society of Cardiology 2010

Principal investigator, steering committee or study coordinator

DSMB member
TALENT study
DESSOLVE III
DESSOLVE-Japan
GIPS-4