Kazuaki Negishi





Prof Kaz Negishi is Professor of Medicine at the University of Sydney; a Cardiologist at Nepean Hospital, NSW; and a current Australian National Heart Foundation Future Leader Fellow. He had his Cardiology training and PhD in Japan, then spent three years in Cleveland Clinic, OH, USA before he came to Australia. He holds Fellowship recognitions from multiple international cardiac societies (FACC, FESC, FAHA, FASE, and FCSANZ).

His cardiovascular imaging interests include early/subclinical stages (A or B) heart failure, including diabetic cardiomyopathy and Cardio-Oncology. The primary modalities used for this are echocardiography (including myocardial strain analysis) and MRI (including T1 mapping). Echocardiography is the frontline tool in cardiology and provides essential information on clinical management. Myocardial strain analysis is a great example of recent advance in echocardiography, which allows early detection of subtle damage in myocardial in various type of cardiovascular diseases. His works have been cited in American and European Guidelines on myocardial strain and Cardio-Oncology.

He is also interested in Environmental Cardiology, especially on air pollution and cardiovascular disease. The adverse effect of air pollution on cardiovascular disease at least equivalent or more than that on respiratory disease. His group reinforced the association between air pollution (PM2.5) and out-of-hospital cardiac arrest (OHCA) among ~250,000 OHCA data. He also identified the lowest threshold of PM2.5 for the increase in heart failure incidence.


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